АНТИПИТАТЕЛЬНЫЕ ФАКТОРЫ В РАСТИТЕЛЬНОМ СЫРЬЕ И ПУТИ СНИЖЕНИЯ ИХ СОДЕРЖАНИЯ
Аннотация и ключевые слова
Аннотация:
Растительное сырье – ключевой источник питательных веществ для человека и животного. Однако пищевая ценность продуктов растительного происхождения ограничена наличием антипитательных веществ (антинутриентов). Цель исследования – собрать и систематизировать современные данные об основных антипитательных веществах, их влиянии на организм человека и эффективных способах снижения уровня таких соединений в пищевых системах растительного происхождения. Объектами исследования являлись научные статьи российских и зарубежных ученых, находящиеся в открытом доступе. Поиск осуществляли по информационным базам PubMed, eLIBRARY.RU, CyberLeninka и с помощью поисковой системы Google Scholar. Период поиска – с 2021 по 2026 гг. Для систематизации найденной информации использовали методы анализа, сравнения и описания. В работе проанализированы основные классы антипитательных соединений: ингибиторы ферментов (протеаз и α-амилазы), фитиновая кислота (фитаты), лектины, танины и сапонины. Описаны их химическая природа, источники и двойственная физиологическая роль, связанная с негативным воздействием на биодоступность и усвояемость макро- и микронутриентов, а также с потенциальной пользой для организма (антиоксидантные, противовоспалительные и гипогликемические свойства) в контролируемых концентрациях. Оценена эффективность традиционных способов (замачивание, проращивание, ферментация, термическая обработка) и инновационных технологий (экструзия, обработка ультразвуком, высоким гидростатическим давлением и импульсным электрическим полем) для снижения содержания антинутриентов. Проведенный анализ традиционных и новых методов показывает необходимость использования комбинированных технологий обработки растительных пищевых систем для эффективного устранения антипитательных факторов и максимального сохранения полезных компонентов как условия повышения их пищевой ценности.

Ключевые слова:
Антипитательные вещества, растительное сырье, ингибиторы ферментов, фитаты, лектины, танины, сапонины, обработка, пищевая ценность
Список литературы

1. Боков Д. О., Богачук М. Н., Малинкин А. Д., Назарова В. А., Бессонов В. В. Оценка взаимодействия полисахаридов и минорных биологически активных веществ в функциональных пищевых ингредиентах растительного происхождения. Вопросы питания. 2023. Т. 92. № 1. С. 108–115. https://doi.org/10.33029/0042-8833-2023-92-1-108-115

2. Han R, Wang Y, Yang Z, Micklethwaite S, Mondor M, et al. Industrial-scale fractionation of fava bean, chickpea, and red lentil: A comparative analysis of composition, antinutrients, nutrition, structure, and functionality. Current Research in Food Science. 2025;11:101152. https://doi.org/10.1016/j.crfs.2025.101152

3. Affrifah NS, Uebersax MA, Amin S. Nutritional significance, value‐added applications, and consumer perceptions of food legumes: A review. Legume Science. 2023;5(4):e192. https://doi.org/10.1002/leg3.192

4. Didinger C, Thompson HJ. The role of pulses in improving human health: A review. Legume Science. 2022;4(4):e147. https://doi.org/10.1002/leg3.147

5. Samtiya M, Aluko RE, Dhewa T. Plant food anti-nutritional factors and their reduction strategies: An overview. Food Production, Processing and Nutrition. 2020;2:6. https://doi.org/10.1186/s43014-020-0020-5

6. Костюченко М. Н., Тагиев Н. Ш., Савкина О. А. Пищевая ценность и антипитательные факторы цельнозерновых ингредиентов для производства хлебобулочных изделий. Хлебопродукты. 2023. № 7. С. 36–40. https://doi.org/10.32462/0235-2508-2023-32-7-36-40

7. Acquah C, Ohemeng-Boahen G, Power KA, Tosh SM. The effect of processing on bioactive compounds and nutritional qualities of pulses in meeting the sustainable development goal 2. Frontiers in Sustainable Food Systems. 2021;5:681662. https://doi.org/10.3389/fsufs.2021.681662

8. Ахангаран М., Афанасьев Д. А., Чернуха И. М., Машенцева Н. Г., Гаравири М. Биоактивные пептиды и антипитательные вещества нута: характеристика и свойства (обзор). Труды по прикладной ботанике, генетике и селекции. 2022. Т. 183. № 1. С. 214–223. https://doi.org/10.30901/2227-8834-2022-1-214-223

9. Kheto A, Choudhury DB, Sarkhel S, Sarkar A, Kumar Y. Anti-nutritional factors: Nutrient interactions, processing interventions, and health aspects. Food Chemistry. 2025;496:146746. https://doi.org/10.1016/j.foodchem.2025.146746

10. Das G, Sharma A, Sarkar PK. Conventional and emerging processing techniques for the post-harvest reduction of antinutrients in edible legumes. Applied Food Research. 2022;2(1):100112. https://doi.org/10.1016/j.afres.2022.100112

11. Salim R, Nehvi IB, Mir RA, Tyagi A, Ali S, et al. A review on anti-nutritional factors: Unraveling the natural gateways to human health. Frontiers in Nutrition. 2023;10:1215873. https://doi.org/10.3389/fnut.2023.1215873

12. Manzanilla-Valdez ML, Ma Z, Mondor M, Hernández-Álvarez AJ. Decoding the duality of antinutrients: Assessing the impact of protein extraction methods on plant-based protein sources. Journal of agricultural and food Chemistry. 2024;72(22):12319–12339. https://doi.org/10.1021/acs.jafc.4c00380

13. Luo Z, Zhu Y, Xiang H, Wang Z, Jiang Z, et al. Guo Advancements in inactivation of soybean trypsin inhibitors. Foods. 2025;14(6):975. https://doi.org/10.3390/foods14060975

14. Shi L, Mu K, Arntfield SD, Nickerson MT. Changes in levels of enzyme inhibitors during soaking and cooking for pulses available in Canada. Journal of Food Science and Technology. 2017;54(4):1014–1022. https://doi.org/10.1007/s13197-017-2519-6

15. Nath H, Samtiya M, Dhewa T. Beneficial attributes and adverse effects of major plant-based foods anti-nutrients on health: A review. Human Nutrition & Metabolism. 2022;28:200147. https://doi.org/10.1016/j.hnm.2022.200147

16. Cheng S, Langrish TAG. A review of the treatments to reduce anti-nutritional factors and fluidized bed drying of pulses. Foods. 2025;14(4):681. https://doi.org/10.3390/ foods14040681

17. Lin Q, Qiu C, Li X, Sang S, McClements DJ, et al. The inhibitory mechanism of amylase inhibitors and research progress in nanoparticle-based inhibitors. Critical Reviews in Food Science and Nutrition. 2022;63(33):12126–12135. https://doi.org/10.1080/10408398.2022.2098687

18. Brouns F. Phytic acid and whole grains for health controversy. Nutrients. 2021;14(1):25. https:// doi.org/10.3390/nu14010025

19. Chondrou T, Adamidi N, Lygouras D, Hirota SA, Androutsos O, et al. Dietary phytic acid, dephytinization, and phytase supplementation alter trace element bioavailability-a narrative review of human interventions. Nutrients. 2024;16(23):4069. https://doi.org/10.3390/nu16234069

20. Singh P, Pandey VK, Sultan Z, Singh R, Dar AH. Classification, benefits, and applications of various anti-nutritional factors present in edible crops. Journal of Agriculture and Food Research. 2023;14:100902. https://doi.org/10.1016/j.jafr.2023.100902

21. Feizollahi E, Mirmahdi RS, Zoghi A, Zijlstra RT, Roopesh MS, et al. Review of the beneficial and anti-nutritional qualities of phytic acid, and procedures for removing it from food products. Food Research International. 2021;143:110284. https://doi.org/10.1016/j.foodres.2021.110284

22. Naithani S, Komath SS, Nonomura A, Govindjee G. Plant lectins and their many roles: Carbohydrate-binding and beyond. Journal of Plant Physiology. 2021;266:153531. https://doi.org/10.1016/j.jplph.2021.153531

23. López-Moreno M, Garcés-Rimón M, Miguel M. Antinutrients: Lectins, goitrogens, phytates and oxalates, friends or foe? Journal of Functional Foods. 2022;89:104938. https://doi.org/10.1016/j.jff.2022.104938

24. Duraiswamy A, Sneha A NM, Jebakani K S, Selvaraj S, Pramitha J L, et al. Genetic manipulation of anti-nutritional factors in major crops for a sustainable diet in future. Frontiers in Plant Science. 2023;13:1070398. https://doi.org/10.3389/fpls.2022.1070398

25. Mazalovska M, Kouokam JC. Plant-derived lectins as potential cancer therapeutics and diagnostic tools. BioMed Research International. 2020;2020:1631394. https://doi.org/10.1155/2020/1631394

26. Timilsena YP, Phosanam A, Stockmann R. Perspectives on saponins: Food functionality and applications. International Journal of Molecular Sciences. 2023;24(17):13538. https://doi.org/10.3390/ijms241713538

27. Sharma K, Kaur R, Kumar S, Saini RK, Sharma S, et al. Saponins: A concise review on food related aspects, applications and health implications. Food Chemistry Advances. 2023;2:100191. https://doi.org/10.1016/j.focha.2023.100191

28. Jan N, Hussain SZ, Naseer B, Bhat TA. Amaranth and quinoa as potential nutraceuticals: A review of anti-nutritional factors, health benefits and their applications in food, medicinal and cosmetic sectors. Food Chemistry: X. 2023;18:100687. https://doi.org/10.1016/j.fochx.2023.100687

29. White CS, Dilger RN. Immunomodulatory potential of dietary soybean-derived saponins. Journal of Animal Science. 2024;102:349. https://doi.org/10.1093/jas/skae349

30. Melo LFM, Aquino-Martins VGQ, Silva APD, Oliveira Rocha HA, Scortecci KC. Biological and pharmacological aspects of tannins and potential biotechnological applications. Food Chemistry. 2023;414:135645. https://doi.org/10.1016/j.foodchem.2023.135645

31. Cosme F, Aires A, Pinto T, Oliveira I, Vilela A, et al. A comprehensive review of bioactive tannins in foods and beverages: functional properties, health benefits, and sensory qualities. Molecules. 2025;30(4):800. https://doi.org/10.3390/molecules30040800

32. Molino S, Pilar Francino M, Rufián Henares MÁ. Why is it important to understand the nature and chemistry of tannins to exploit their potential as nutraceuticals? Food Research International. 2023;173:113329. https://doi.org/10.1016/j.foodres.2023.113329

33. Ojo MA. Tannins in foods: nutritional implications and processing effects of hydrothermal techniques on underutilized hard-to-cook legume seeds-a review. Preventive Nutrition and Food Science. 2022;27(1):14–19. https://doi.org/10.3746/pnf.2022.27.1.14

34. Abera S, Yohannes W, Chandravanshi BS. Effect of processing methods on antinutritional factors (oxalate, phytate, and tannin) and their interaction with minerals (calcium, iron, and zinc) in red, white, and black kidney beans. International Journal of Analytical Chemistry. 2023;2023:6762027. https://doi.org/10.1155/2023/6762027

35. Rizvi QUEH, Guiné RPF, Ahmed N, Sheikh MA, Sharma P, et al. Kumar Effects of soaking and germination treatments on the nutritional, anti-nutritional, and bioactive characteristics of adzuki beans (Vigna angularis L.) and lima beans (Phaseolus lunatus L.). Foods. 2024;13(9):1422. https://doi.org/10.3390/foods13091422

36. Ким А. А., Баланов П. Е., Смотраева И. В. Влияние ферментации бобовых на снижение антипитательного фактора. Обзор. Пищевые системы. 2025. Т. 8. № 3. С. 401–406. https://doi.org/10.21323/2618-9771- 2025-8-3-401-406

37. Das R, Islam M, Mahajan P, Kaur R, Gaur S, et al. Emerging non-thermal technologies for reducing anti-nutritional factors in food systems: A systematic review. Journal of Food Science. 2025;90(12):e70781. https://doi.org/10.1111/1750-3841.70781

38. Антипова Л. В., Ибрагимова О. Т., Плотников В. Е., Плотникова И. В. Изменение химического состава высокобелковых бобовых культур при проращивании и технологические возможности их применения в функциональных пищевых системах. Вестник ВГУИТ. 2025. Т. 87. № 3. С. 56–65. https://doi.org/10.20914/2310-1202-2025-3-56-65

39. Yılmaz Tuncel N, Polat Kaya H, Sakarya FB, Andaç AE, Korkmaz F, et al. The effect of germination on antinutritional components, in vitro starch and protein digestibility, content, and bioaccessibility of phenolics and antioxidants of some pulses. Food Science & Nutrition. 2025;13(5):e70103. https://doi.org/10.1002/fsn3.70103

40. Плотников В. Е., Магомедов М. Г., Суханов П. Т., Плотникова И. В., Полянский К. К. и др. Антипитательные факторы зернобобовых культур: качественный и количественный анализ танинов в чечевице и продуктах ее переработки. Вестник ВГУИТ. 2025. Т. 87. № 3. С. 141–152. https://doi.org/10.20914/2310-1202-2025-3-141-152

41. Thakur P, Kumar K, Ahmed N, Chauhan D, Eain Hyder Rizvi QU, et al. Effect of soaking and germination treatments on nutritional, anti-nutritional, and bioactive properties of amaranth (Amaranthus hypochondriacus L.), quinoa (Chenopodium quinoa L.), and buckwheat (Fagopyrum esculentum L.). Current Research in Food Science. 2021;4:917–925. https://doi.org/10.1016/j.crfs.2021.11.019

42. Maldonado-Alvarado P, Pavón-Vargas DJ, Abarca-Robles J, Valencia-Chamorro S, Haros CM. Effect of germination on the nutritional properties, phytic acid content, and phytase activity of quinoa (Chenopodium quinoa Willd). Foods. 2023;(2):389. https://doi.org/10.3390/foods12020389

43. Emkani M, Oliete B, Saurel R. Effect of lactic acid fermentation on legume protein properties, a review. Fermentation. 2022;8:244. https://doi.org/https://doi.org/10.3390/fermentation8060244

44. Noori SMA, Hojjati M, Sorourian R. Enhancing nutritional quality and functionality of legumes: Application of solid-state fermentation with Pleurotus ostreatus. Food Science & Nutrition. 2025;13:e70783. https://doi.org/10.1002/fsn3.70783

45. Ayub AR, Waseem M, Ahmad Z, Alshammari JM, Ismail T, et al. Probing the effect of ultrasonication, probiotic lacto-fermentation, and blanching on bioactive compounds, antioxidants activities, and antinutrients of tomato. Food Science & Nutrition. 2025;13:e70970. https://doi.org/10.1002/fsn3.70970

46. Naseem A, Akhtar S, Ismail T, Qamar M, Sattar D. Effect of growth stages and lactic acid fermentation on antinutrients and nutritional attributes of spinach (Spinacia oleracea). Microorganisms. 2023;11:2343. https://doi.org/10.3390/microorganisms11092343

47. Sun X, Ma L, Xuan Y, Liang J. Degradation of anti-nutritional factors in maize gluten feed by fermentation with Bacillus subtilis: A focused study on optimizing fermentation conditions. Fermentation. 2024;10:555. https://doi.org/10.3390/fermentation10110555

48. Yehuala TF, Atlabachew M, Aslam MF, Allen L, Griffith H, et al. Fermentation kinetics and changes in levels of antinutrients in pearl millet and pearl millet-maize composite dough recipes used to prepare Injera. Science & Nutrition. 2025;13(7):e70598. https://doi.org/10.1002/fsn3.70598

49. Avilés-Gaxiola S, Chuck-Hernández C, Serna SO. Inactivation methods of trypsin inhibitor in legumes: A review. Journal of Food Science. 2018;83(1):17–29. https://doi.org/10.1111/1750-3841.13985

50. Pedrosa MM, Guillamón E, Arribas C. Autoclaved and extruded legumes as a source of bioactive phytochemicals: A review. Foods. 2021;10:379. https://doi.org/10.3390/foods10020379

51. Arise AK, Malomo SA, Cynthia CI, Aliyu NA, Arise RO. Influence of processing methods on the antinutrients, morphology and in-vitro protein digestibility of jack bean. Food Chemistry Advances. 2022;1:100078. https://doi.org/10.1016/j.focha.2022.100078

52. Liberal Â, Fernandes A, Ferreira ICFR, Vivar-Quintana AM, Barros L. Effect of different physical pre-treatments on physicochemical and techno-functional properties, and on the antinutritional factors of lentils (Lens culinaris spp). Food Chemistry. 2024;450:139293. https://doi.org/10.1016/j.foodchem.2024.139293

53. Ciudad-Mulero M, Vega EN, García-Herrera P, Fernández-Tomé S, Pedrosa MM. New gluten-free extruded snack-type products based on rice and chickpea and fortified with passion fruit skin: Extrusion cooking effect on phenolic composition, non-nutritional factors, and antioxidant properties. Molecules. 2025;30(6):1225. https://doi.org/10.3390/molecules30061225

54. Duguma HT, Forsido SF, Belachew T, Hense O. Changes in anti-nutritional factors and functional properties of extruded composite flour. Frontiers in Sustainable Food Systems. 2021;5:713701. https://doi.org/10.3389/fsufs.2021.713701

55. Badjona A, Bradshaw R, Millman C, Howarth M, Dubey B. Faba bean processing: Thermal and non-thermal processing on chemical, antinutritional factors, and pharmacological properties. Molecules. 2023;28(14):5431. https://doi.org/10.3390/molecules28145431

56. Yu S, Zhang Yu, Zhang Y, Zhang CH, Liu X, et al. Water-assisted microwave processing: Rapid detoxification and antioxidant enhancement in colored kidney beans. Foods. 2025;14(20):3557. https://doi.org/10.3390/foods14203557

57. Waseem M, Akhtar S, Ismail T, Alsulami T, Qamar M, et al. Effect of thermal and non-thermal processing on Technofunctional, nutritional, safety and sensorial attributes of potato powder. Food Chemistry: X. 2024;24:101896. https://doi.org/10.1016/j.fochx.2024.101896

58. Рождественская Л. Н., Чугунова О. В. Разработка технических решений по снижению антипитательных веществ бобового сырья. Индустрия питания. 2025. Т. 10. № 2. С. 33–45. https://doi.org/10.29141/2500-1922-2025-10-2-4

59. Ohanenye IC, Ekezie FC, Sarteshnizi RA, Boachie RT, Emenike CU. Legume seed protein digestibility as influenced by traditional and emerging physical processing technologies. Foods. 2022;11(15):2299. https://doi.org/10.3390/foods11152299

60. Altıkardeş E, Güzel N. Impact of germination pre-treatments on buckwheat and Quinoa: Mitigation of anti-nutrient content and enhancement of antioxidant properties. Food Chemistry: X. 2024;21:101182. https://doi.org/10.1016/j.fochx.2024.101182

61. Yadav S, Mishra S, Pradhan RC. Ultrasound-assisted hydration of finger millet (Eleusine Coracana) and its effects on starch isolates and antinutrients. Ultrasonics sonochemistry. 2021;73:105542. https://doi.org/10.1016/j.ultsonch.2021.105542

62. Dong G, Hu Z, Tang J, Das RS, Sun DW, et al. Reducing anti-nutritional factors in pea protein using advanced hydrodynamic cavitation, ultrasonication, and high-pressure processing technologies. Food Chemistry. 2025;488:144834. https://doi.org/10.1016/j.foodchem.2025.144834

63. Johnston C, Leong SY, Teape C, Liesaputra V, Oey I. Low-intensity pulsed electric field processing prior to germination improves in vitro digestibility of faba bean (Vicia faba L.) flour and its derived products: A case study on legume-enriched wheat bread. Food Chemistry. 2024;449:139321. https://doi.org/10.1016/j.foodchem.2024.139321


Войти или Создать
* Забыли пароль?